Application of TGF beta pathway inhibitor in preparation of medicine for improving sensitivity of thyroid cancer radioactive iodine therapy
user-5f8cf7e04c775ec6fa691c92(2020)
Abstract
The invention discloses application of a TGF beta pathway inhibitor in preparation of a medicine for improving sensitivity of thyroid cancer radioactive iodine therapy, and belongs to the field of antitumor medicines. The invention further discloses a combined medicine and a pharmaceutical composition for treating radioactive iodine refractory thyroid cancer, and the TGF beta pathway inhibitor andradioactive iodine are used as pharmacodynamic active ingredients. The TGF beta pathway inhibitor can enhance the intake capacity of tumor cells of the thyroid cancer to the radioactive iodine, thereby effectively improving the therapeutic effect of the radioactive iodine, and the TGF beta pathway inhibitor has good market value when applied to the preparation of thyroid medicines.
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Key words
Thyroid cancer,Thyroid,Iodine,TGF beta signaling pathway,Cancer research,Therapeutic effect,Active ingredient,Medicine,Radioactive iodine,Radioactive iodine therapy
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