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Intravenous To Oral Switch In Complicated Staphylococcus Aureus Bacteremia Without Endovascular Infection: A Retrospective Single-Center Cohort Study

Ilse J E Kouijzer,Eline J van Leerdam,Michelle Gompelman,Renee A M Tuinte,Erik H J G Aarntzen,Marvin A H Berrevoets,Ianthe Maat,Chantal P Bleeker-Rovers,Reinout van Crevel,Jaap Ten Oever

CLINICAL INFECTIOUS DISEASES（2021）

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Abstract
In this retrospective cohort study, selected patients with disseminated Staphylococcus aureus bacteremia, but without endovascular infection on echocardiography and F-18-FDG-PET/CT, were free of relapse after IV-oral switch. Mortality was low and similar to patients who received prolonged intravenous treatment. IV-oral switch was associated with a shorter length of hospital stay.
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Staphylococcus aureus, bacteremia, treatment, IV-oral switch
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