Aorta, Liver, And Portal Vein Ct Contrast Enhancement During The Portal Venous Phase Are Positively Associated With Abdominal Fat Percentage In Dogs

VETERINARY RADIOLOGY & ULTRASOUND(2021)

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摘要
Contrast-enhanced computed tomography (CT) is increasingly being used as a standard diagnostic test for dogs with suspected abdominal pathology. The iodinated contrast dose is commonly calculated based on linear increases in total body weight. However, body fat is not metabolically active and contributes little to dispersing or diluting the contrast medium in the blood. The aim of this retrospective single-center analytic study was to investigate the possible correlation between abdominal organ and vessel enhancement, and abdominal fat percentage in dogs. We hypothesized that, when dosing intravenous iodinated contrast according to total body weight, there would be a positive association between the degree of contrast enhancement of selected organs and vessels with increasing abdominal fat percentage. Vascular and parenchymal attenuation data were collected from 62 multiphasic abdominal CECT scans performed on dogs over a 5-year period at U-Vet Werribee Animal Hospital between February 2014 and February 2019. Findings based on a linear regression model showed a positive association of aorta (P = .005), liver (P = .045), and portal vein (P = .001) enhancement to abdominal fat percentage during the portal venous phase. Authors recommend that other body size parameters, such as lean body weight, should be considered when calculating iodine dose for abdominal contrast-enhanced CT in dogs.
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关键词
abdomen, canine, iodinated contrast, Iohexol, obesity, LBW lean body weight, CECT contrast&#8208, enhanced computed tomography
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