Astragaloside IV ameliorates steroid-induced osteonecrosis of the femoral head by repolarizing the phenotype of pro-inflammatory macrophages
International Immunopharmacology（2021）
Abstract
•AS-IV repolarizes macrophages from M1 to M2 phenotypes.•Culture medium from AS-IV treated M1 macrophages suppresses cell apoptosis.•AS-IV decreases the ratio of M1 macrophages in the femoral head.
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Key words
Astragaloside IV,Osteonecrosis of the femoral head,Macrophages,Repolarization,Inflammation
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