[Exploration of the correlation between allergic rhinitis and weather factors in Nanning].

Objective:To investigate the characteristics of allergic rhinitis（AR） in the Nanning area and its correlation with meteorological factors. Methods:The characteristics of 16 969 cases of AR in Nanning from May 2011 to June 2018 were analyzed. Meteorological parameters were collected from the official website of the Nanning Meteorological Bureau, including weather conditions, temperature, and wind direction. The relationship between the onset characteristics of AR patients and meteorological factors were also analyzed. Results:Among the 16 969 patients with AR, the top three inhalation allergens were dust mite（56.0%）, house dust mite（50.5%）, and cockroach（37.4%）. The skin index（SI） of dust mite, house dust mite, cockroach is correlated with sex. The SI of dust mite, house dust mite, mugwort, cockroach are correlated with age, and inhaled allergens are correlated with disease course（P<0.05）. However, those relationships were not significant（r<0.2）. The proportion of AR patients visiting the clinic in summer was the highest（3.9%） in all of the four seasons. Gender was found to be related to the grade-4 positive results of dust mite（OR=0.826, 95%CI: 0.724-0.942）, the grade-4 house dust mite（OR=0.777, 95%CI: 0.677-0.891） and the grade-3 positive results of cockroach（OR=1.236, 95%CI: 1.060-1.443）, respectively. The the daytime weather conditions were related to the grade-4 positive results of dust mite（OR=0.830, 95%CI: 0.728-0.947） and the grade 1 positive results of house dust mite（OR=0.803, 95%CI: 0.694-0.929）, respectively. The highest temperature was related to the grade-4 positive result of dust mite（OR=1.032, 95%CI: 1.020-1.043）, grade-1（OR=1.028, 95%CI: 1.001-1.056） and grade-4 （OR=1.047, 95%CI: 1.021-1.075） positive result of house dust mite, grade 1（OR=1.023, 95%CI: 1.001-1.047） and grade-4（OR=1.050, 95%CI: 1.008-1.094） positive result of cockroach, respectively. The minimum temperature was related to the positive results of house dust mites at all grades and the grade-1 positive results of cockroach（OR=0.947, 95%CI: 0.924-0.971）, but not to dust mites. The daytime wind direction was related to the grade-3 positive results of cockroach（OR=1.437, 95%CI: 1.157-1.785）. Conclusion:The number of AR patients in Nanning is highest in summer. The female is more likely to suffer from dust mite and house dust mite, while the male is more likely to suffer from cockroach. Meteorological factors are correlated with the incidence of AR.The highertemperature, the rain and the southerly wind could cause the occurrence or aggravation of AR.