In-situ grafting temperature-responsive hydrogel as a bifunctional solid-phase microextraction coating for tunable extraction of biomacromolecules

Jian-Bo Qu,Yang-Yang Lin,Qing Li,Wen-Shu Peng,Jiankun Huang,Jing Li,Benjamin Edem Meteku,Jingbin Zeng

Journal of Chromatography A（2021）

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摘要

lThermo-responsive bifunctional SPME coating was prepared via in-situ ATRP method.lEnrichment of polar/non-polar analytes was achieved by altering temperature.lExtraction capacity of the coating for BSA at 50°C is about 3 fold that of 15°C.

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关键词

SPME,In-situ grafting,Temperature-responsive extraction,Polar and non-polar analytes,Biomacromolecules

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