Acute Lymphoblastic Leukemia Cell Lines In Immunology Research

Salvador Valle-Reyes,Oxana Dobrovinskaya,Rosana Pelayo,Michael Schnoor

TRENDS IN IMMUNOLOGY（2021）

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摘要

A considerable portion of our knowledge on T and B cell biology is acquired from research using acute lymphoblastic leukemia (ALL) cell lines, which are invaluable tools used in many immunology and leukemia studies. Here, we discuss the advantages and limitations of ALL cell lines and provide guidelines on their proper usage.

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