A case report on the first confirmed case of PNH in Ethiopia : PNH

PNH is an acquired hemolytic disorder caused by somatic mutation characterized by intravascular hemolysis with pancytopenia and a tendency to thrombosis. It is a rare disease with incidence of 1 to 10 cases per million populations. We are reporting the first confirmed case of PNH in Ethiopia. He is a 38 years old man who presented with anemia and jaundice of 3 years duration; he has mild pallor; lab examinations showed moderate anemia with features of coomb’s negative intravascular hemolysis; and finally very large clone of PNH cells on immunophenotypic analysis