Multicomponent Synthesis Of Highly Functionalized Piperidines

Highly functionalized piperidines are a versatile class of nitrogen-containing heterocycles which find broad applications in numerous fields such as medicinal chemistry and drug discovery research. The synthesis of this privileged scaffold from readily available materials remains is a hot topic research for the synthetic chemistry community. This review aims to describe the different strategies developed so far for the synthesis of highly functionalized piperidines.