Comparison of CO2 Laser and Cryotherapy for Clinical Improvement in Vascular Tumor Lesions in Patients with Klippel Trenaunay Syndromes: A Rare Case

Pipim Septiana Bayasari,Khairuddin Djawad,Airin R. Nurdin, Idar Mappangara, Paskalis Indra Suryajaya

Systematic Reviews in Pharmacy(2020)

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摘要
Klippel Trenaunay\u0027s syndrome (KTS) has three main characteristics: (1) varicose veins; (2) hypertrophy (soft tissue, bone); and (3) malformations (veins, capillaries). Hemangioma is a vascular anomaly in the form of endothelial cell tumors accompanied by cell hyperplasia. Vascular doppler examination and MSCT-scan arteriography found venous malformations, soft tissue thickening, capillary malformations and varicose veins which support the diagnosis of KTS syndrome. One case was reported, a 29-year-old male treated with a CO2 Laser (frequency 500; fluence 20ml; energy 63.69 J / cm2), combined Laser CO2 (frequency 500; fluence 20ml; energy 63.69 J / cm2) with Timolol maleate 0.5% every 4 hours occlusive and cryotherapy for hemangioma lesions. Significant improvement in lesions was obtained with the use of cryotherapy with a low recurrence rate compared to the use of CO2 laser.
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klippel trenaunay syndromes,vascular tumor lesions,co2 laser,cryotherapy
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