Grey Relation between Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus with Secondary Malignancy

Objective: To investigate the relation between blood glucose and serum lipids level in type 2 diabetes mellitus (T2DM) patients with secondary malignancy by grey relational analysis. Methods: A total of 148 T2DM patients with secondary malignancy were enrolled as the patient group and were 1:1 paired by non-malignancy simultaneously according to sex, age and diabetic duration used as the control group. Two groups were further divided into optimal and poor blood glucose control (BGC) by the level of HbA1C. Raw data of HbA1C and serum lipids were treated with mean measurement. Grey relational grade between HbA1C and serums lipids (total cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein) were calculated. Results: The grey relational order (GRO) of poor BGC in patient group was TG > HDL> TC> LDL, and LDL> TG> TC> HDL in control group. Conclusion: There was no difference in GRO of optimal BGC between two groups. The grey relation between poor BGC and serum lipids level in patient group is different from that in control group. TG Level was the strongest grey relation with poor BGC in malignancy.