Central serotonin participates in the anorexigenic effect of GLP-1 in rainbow trout (Oncorhynchus mykiss)

General and Comparative Endocrinology(2021)

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摘要
•Peripherally injected Glucagon-like Peptide-1 inhibits food intake in rainbow trout.•Activation of central serotoninergic system occurs after a GLP-1 treatment.•5HT2C receptors are essential to the reduction of food intake promoted by GLP-1.
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关键词
Glucagon-like Peptide-1,Serotonin,Food intake,Hypothalamus,Rainbowtout
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