Rise of antimicrobial resistance in Klebsiella spp. in a country town of Rio Grande do Sul, Brazil
REVISTA DE EPIDEMIOLOGIA E CONTROLE DE INFECCAO(2017)
摘要
Background and Objectives: Several infections by multidrug-resistant Klebsiella spp. have been report worldwide, because of the capacity of these bacteria in acquire many resistance mechanisms and rapidly spread through clinical units. The aim of this study was evaluate the antimicrobial susceptibility profile of Klebsiella spp. in a hospital of a country town of Rio Grande do Sul, Brazil. Methods: This study investigated the resistance profile of Klebsiella spp. strains isolated between 2014 and 2015, in a regional hospital of a small town. The patient's charts and microbiological assays were review, including age, sex, date, anatomical site of isolation, origin, and antimicrobial susceptibility test. Results: Forty-two strains were isolated during 2014 and 2015. The positive cultures were from urine (57%), secretions (38%), and blood (5%). Was observed antibiotic resistance in 81% of the strains, and 62% showed multidrugresistance. The resistance profile for beta-lactams, mainly cefalosporin and carbapenem, and for aminoglycosides and tetracycline increased in the study period. Conclusion: In this study we showed an increase in antibiotic resistance in a hospital at a small town, highlighting the emergence of carbapenem resistant Klebsiella spp. during 2015. The spread of multidrug-resistant bacteria in this hospital enhance the importance of epidemiological surveillance and establishment of infection control procedures.
更多查看译文
关键词
Klebsiella,Drug Resistance,Microbial,Carbapenems,Cross Infection,Infection Control
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要