Effect of a strength training program on IGF-1 in older adults with obesity and controlled hypertension

Introduction: As people age, muscles decrease in size and strength. Loss of muscle mass can cause a general decrease of metabolic function associated with low anabolic hormone production and risk of injury. The decrease in serum levels of GH and IGF-1 due to aging can provoke fragility by contributing to the loss of muscle mass and strength. Purpose: To determine the effect of a strength training program on IGF-1 in older adults with obesity and controlled hypertension. Method: a sample of 8 older adults with obesity and controlled hypertension performed 6 weeks of strength training with intensities of 70% 1RM and 10RM, with a frequency of 4 times per week. Prior to the protocol of Training, triglycerides, cholesterol, blood glucose IGF-1, and anthropometric measures (size, weight, % fat and muscle mass) were determined. The test of one maximum repetition (1rm) was performed to evaluate maximum force in upper and lower limbs before and after the training program. Results: A significant increase (p<0.05) was observed in serum IGF-1 levels after the completion of training program. Conclusion: Strength training with intensities of 70% of 1RM and frequency of 4 days/week, carried out for 6 weeks, produced increases in serum IGF-1 concentration and increased muscle strength in older adults with obesity and controlled hypertension.