Cyanide Ion-Promoted Nucleophilic Displacement Of Aromatic Nitro Groups: A Mild, One-Pot, Transition Metal-Free Synthesis Of Nitrile-Containing Naphthalimide Aryl Ether Derivatives

Herein we report the novel synthesis of nitrile-containing naphthalimide aryl ether derivatives via transition metal-free cyanide ion-promoted nucleophilic displacement of nitronaphthalimide with alcohols or phenols. The transformation involves a one-pot reaction, which is operationally simple and mild and bereft of transition metal catalysts. This work provides a novel route for the preparation of diary! ether derivatives.