MiR-222-3p downregulation prompted the migration, invasion and recruitment of endothelial progenitor cells via ADIPOR1 expression increase-induced AMKP activation

Microvascular Research（2021）

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摘要

•Inhibiting miR-222-3p expression facilitated the repair of rat aneurysm.•ADIPOR1 was the target gene of miR-222-3p.•Downregulated miR-222-3p prompted the migration and recruitment of EPCs by targeting ADIPOR1-induced AMKP activation.

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关键词

miR-222-3p,Endothelial progenitor cells,Abdominal aortic aneurysm,Migration,Invasion,ADIPOR1,AMKP signaling pathway

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