Distinct cell death markers identified in critical care patient survivors diagnosed with sepsis
Immunology Letters(2021)
Abstract
•Decrease in serum caspase-1 and p62 in sepsis survivor patients compared to healthy controls.•Decrease in serum caspase-1 and MLKL compared to caspase-3 in sepsis survivor patients.•Basal levels of serum caspase-3, caspase-1, MLKL and p62 are not different in healthy controls.•Altered expression of cell death markers in PBMCs from septic survivors versus healthy controls.
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Key words
Sepsis,Cell death,caspase-3,caspase-1,MLKL, p62/SQSTM1
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