Cholesterol: Bioactivities, Structural Modification, Mechanisms Of Action, And Structure-Activity Relationships
MINI-REVIEWS IN MEDICINAL CHEMISTRY(2021)
Abstract
Cholesterol, steroid alcohol, was discovered by M.E. Chevreul in 1815. Cholesterol and its derivatives showed a large variety of biological properties such as anticancer activity, anticardiac ac-tivity, anti-inflammatory activity, antimicrobial activity, anti-psychotic activity, antioxidant activity, drug-loaded activity, etc. In this mini-review, the advances of structural modification of cholesterol from 2014 to 2020 are summarized. In addition, the bioactivities, mechanisms of action and structure-activity relationships of cholesterol and its related derivatives are also discussed.
MoreTranslated text
Key words
Cholesterol derivatives, biological activities, structural modification, mechanisms of action, structure-activity relationships
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined