Multivariate investigations of electrophysiological indices for the diagnosis and prognosis of schizophrenia

Our understanding of the nature and aetiological architecture of psychotic mental disorders has advanced notably in the past 20 years. It is now widely considered that psychotic disorders occur as consequence of a complex range of factors, spanning multiple domains and levels, that act on several psychological and biological mechanisms. In recent years, evidence has accumulated that exposure to, broadly, adverse social conditions and experiences over the course of development constitute part of this complex array of factors that influence onset. In this chapter, we will provide a critical overview of this evidence, including consideration of outstanding conceptual and methodological issues that limit the causal inferences that can be drawn from existing findings. From this, we will propose and sketch a sociodevelopmental pathway—as one of several pathways—to psychoses.