17516 Clinical and histologic evaluation of the phenol-croton oil peel versus phenol-oleic acid peel for neck rejuvenation in a split-neck study

Introduction: Neck rejuvenation is one of the most challenging cosmetic subjects for dermatologists. Phenol-croton oil peel is considered the standard for deep facial resurfacing do to the ability of the combination of phenol, soap, croton oil and water to reach the reticular dermis. Pain, scarring, persistent erythema, hyperchromia, and postinflammatory hypochromia are some of the complications that may occur. Croton oil is an irritant used to increase the penetration of phenol. Oleic acid is a fatty acid with high penetration through the hydrophobic layer like skin. It has been used as a penetration enhancer for various enzymes, drugs or other macromolecules.