Solubilisation of salicylate in F127 micelles: Effect of pH and temperature on morphology and interactions with cyclodextrin

Journal of Molecular Liquids(2021)

引用 10|浏览14
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摘要
The present work examines the behavior of salicylic acid (SAL)-loaded F127 micelles as drug nanocarriers for controlled release by means of interaction with 2,6-dimethyl-β-cyclodextrin (DIMEB) in the intestine at basic pH = 7–8, both important excipients, of pharmaceutical formulations.
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关键词
Salicylic acid (SAL),Pluronic® F127,2,6- dimethyl β-cyclodextrin (DIMEB),Cylindrical micelles,Controlled release,Small angle neutron scattering (SANS), fluorescence spectroscopy
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