Anticancer and antibacterial properties of trinuclear Cu(I), Ag(I) and Au(I) macrocyclic NHC/urea complexes

Christian H.G. Jakob,Angela Weigert Muñoz,Jonas F. Schlagintweit,Vanessa Weiß,Robert M. Reich,Stephan A. Sieber,João D.G. Correia,Fritz E. Kühn

Journal of Organometallic Chemistry（2021）

Cited 26|Views10

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Abstract

•Synthesis of novel trinuclear macrocyclic NHC/urea Cu, Ag, Au complexes•Antiproliferative activity against cervix (HeLa) and breast (MCF7) cancer cell lines•Activity against Gram-positive (S. aureus) and -negative (E. coli) bacteria strains•Evaluation of luminescent properties for potential fluorescence microscopy studies

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Key words

Anticancer,antibacterial,N-heterocyclic carbene,fluorescence,coinage metals

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