Non-infectious neutrophilic and pustular dermatoses

This article reviews non-infectious inflammatory dermatoses with mainly neutrophilic infiltrates and the formation of pustules. The infiltrate containing neutrophils may either be mild as in urticaria or very dense, even with leukocytoclasia as in Sweet syndrome or pyoderma gangrenosum. The location, interaction with epithelial structures and density of the neutrophilic infiltrate may be useful to distinguish these dermatoses. Neutrophilic infiltrates and pustular eruptions are caused by different non-infectious immunomechanisms. Neutrophilic dermatoses are of high interest, as they may present dermatological reaction patterns of underlying benign or malignant conditions.