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Oxidative Stress Promotes Susceptibility To Atrial Fibrillation In Pitx2 Deficient Mice

Kyungsoo Kim,Tuerdi Subati,Matthew B. Murphy,Joseph C. Van Amburg,Isis L. Christopher,Joyce E. Johnson,Joey V. Barnett,Dan M. Roden,Katherine T. Murray

Circulation（2020）

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Abstract
Introduction: The strongest genetic risk factor for atrial fibrillation (AF) is variants on chromosome 4q25, near the paired-like homeobox transcription factor 2 gene Pitx2. Mice deficient in Pitx2...
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