Phosphorus-containing star-shaped polymer conjugates for biomedical applications
European Polymer Journal(2021)
摘要
•A novel star-shaped polymer with oligo(oxyethylene H-phosphonate) arms was obtained.•Star-shaped polyphosphoramidates bearing glucopyranosyl or AZT residues were obtained.•The star-shaped glycopolymer forms complexes with the lectin Concanavalin A.•AZT conjugate displayed sustained release of the active compound over a period of 48 h.
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关键词
Polyphosphoramidate,Star-shaped glycopolymer,AZT conjugate,Staudinger reaction,Cytotoxicity
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