Cytokines, Chemokines And Growth Factors Concentration In Bal Fluid Frompatients With Idiopathic Pulmonary Fibrosis (Ipf) And Nonspecific Interstitial Pneumonia (Nsip)

Introduction: Aberrant wound healing in respiratory epithelium and excessive extracellular matrix deposition in interstitium are the main pathogenic mechanisms leading to lung fibrosis. Protein mediators driving these phenomena are poor characterized. A number of serum and bronchoalveolar lavage (BAL) transcriptomic data is emerging, but it is uncertain whether changes in mRNA reflect those of the protein mediators.