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Epigenetic aspects of DC development and differentiation

Heike Chauvistré,Kristin Seré

Molecular Immunology（2020）

Cited 4|Views10
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Abstract
•Epigenetic mechanisms allow high-end fine tuning and flexibility of gene expression.•DC genes are epigenetically primed in DC precursors.•The repertoire of active enhancers is highly cell type specific.•Various enhancers transiently contribute to Irf8 expression during DC lineage development.
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Key words
Gene expression regulation,Dendritic cells,Histones,Enhancers,Epigenetic mechanisms,Chromatin accessibility
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