Selective synthesis of functionalized quinazolinone derivatives via biocatalysis
Molecular Catalysis（2020）
Abstract
A novel and efficient biocatalyzed methodology for the construction of functionalized quinazolinone derivatives via tandem / hydrolysis / decarboxylation / cyclization and transesterification reactions has been developed that works with a variety of 2-aminobenzamide and β-dicarbonyl compounds.
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Key words
Quinazolinone derivatives,Biocatalysis selective synthesis,Green chemistry,Decarboxylation,Tandem reaction
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