Circulating Tumor Dna Dynamics Predict Outcomes Of Systemic Therapy In Patients With Advanced Cancers

M. Gouda,H. Huang,S. Piha-Paul,S.G. Call,D. Karp, S. Fu,A. Naing,V. Subbiah,S. Pant,A.M. Tsimberidou,D.S. Hong, J. Rodon, F. Meric-Bernstam

EUROPEAN JOURNAL OF CANCER（2020）

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摘要

Background: Detection of molecular alterations in circulating tumor DNA (ctDNA) has been recently established as a tool to detect molecular targets for cancer therapy. Preliminary data suggest that dynamic changes in ctDNA quantity can be associated with outcomes of cancer therapy.

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advanced cancers,systemic therapy,dna,tumor

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