Automated measurement of pH-dependent solid-liquid equilibria of itaconic acid and protocatechuic acid

Arne Holtz,Jonas Görtz,Christian Kocks, Mark Junker,Andreas Jupke

Fluid Phase Equilibria（2021）

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摘要

•Solubility measurement in complex media without development of offline analytics.•Monitoring the dissolution of solids via FBRM avoids entering the metastable zone.•Identification of equilibrium influencing parameters by fast collection of data.

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关键词

Solubility,pH shift crystallization,Electrolyte influence,2-Methylidenebutanedioic acid,3,4-Dihydroxybenzoic acid

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