Interleukin-7 Receptor Gene Heterozygous Mutations In Recipients Significantly Increase Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
BLOOD(2020)
Abstract
Acute graft-versus-host disease (aGVHD) is one of major complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Genetic polymorphisms of interleukin-7 receptor (IL-7R) have an impact on transplant-related mortality (Z Shamim et al. BMT 2006). Our previous studies indicated that hematological and immunological hereditary predisposition genes have potential influence on major complications of allo-HSCT in patients with hematological malignancies (unpublished data).
MoreTranslated text
Key words
transplantation,graft-versus-host
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined