Impact Of Diabetes In Patients With Copd

Introduction: Comorbidities during chronic obstructive pulmonary disease (COPD) can influence the prognosis independently. Among these comorbidities is diabetes. Aim: To determine the characteristics of COPD in diabetic patients. Methods: We conducted a retrospective study of patients admitted with a diagnosis of COPD between January 2015 and December 2019. Clinical and biological characteristics data on admission were recorded. Patients were divided into two groups: Group1 (G1): patients with diabetes (n=40); Group 2 (G2): patients without diabetes (n=132). Results: A total of 172 patients were included. The sex ratio was 6.8 and the mean age was 67.75 ± 10.55 years. Eighteen percent of the patients had diabetes. Statistical analysis showed that high blood pressure was significantly more frequent in G1 (55.6%) than in G2 (22%); p=0.01. Obstructive sleep apnea was also significantly more frequent in G1 (G1: 6.5%, G2: 0%, p=0.032) as well as dyslipidemia (G1: 16.1%, G2: 2.8%, p=0.01), osteoporosis (G1:12.9%, G2: 2.8%, p=0.036) , history of stroke G1 (G1: 16.1%, G2: 7%, p=0.038) and non-cystic fibrosis (G1: 12.9%, G2:2.9%, p=0.038). FEV1 was significantly lower in G1 (1.04 l ± 0.45) compared to G2 (0.65±0.45) (p=0.06). There was no significant difference between the two groups in exacerbations and hospitalizations rates (p>0.05). Conclusion: According to our study, in the COPD population, diabetes seems to be associated with more comorbidities and a worse respiratory function while it does not increase exacerbations rate.