Does Phlebotomy for Donor Purposes in Healthy People have Effects on Total Oxidant and Total Antioxidant levels

Purpose: In this study, we aimed to evaluate the possible long-term effects of phlebotomy on body oxidant and antioxidant system in healthy people. Materials and Methods: This prospective study included 30 healthy volunteers (15 men and 15 women) who applied to donate blood to the Red Crescent Blood Center. Total antioxidant capacity, total oxidant status, oxidative stress index, hemoglobin, unsaturated iron binding capacity, iron and ferritin levels were measured before the phlebotomy and on the 14th day following the procedure. Results: The levels of total antioxidant capacity, total oxidant status, oxidative stress index, hemoglobin, unsaturated iron binding capacity, and iron values showed no statistically significant difference before and after the procedure (p> 0.05). Hemoglobin and ferritin values showed statistically significant difference before and after the procedure. Conclusion: It seems that single-season phlebotomy has no long-term effect on the body total oxidant and antioxidant levels.