Combination Of Ibrutinib With Rituximab (Ir) In Previously Untreated Older Patients With Mantle Cell Lymphoma (Mcl) - A Phase Ii Clinical Trial
BLOOD(2020)
摘要
Background - Older patients (pts) with mantle cell lymphoma (MCL) may exhibit poor functional status and become ineligible for intensive chemo-immunotherapy or stem cell transplantation. The advent of chemotherapy-free therapies are a significant advance in MCL. We investigated the safety and efficacy of combining ibrutinib and rituximab (IR) in previously untreated older pts (age ≥65 years) with MCL in a single center, phase II clinical trial.
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关键词
Mantle Cell Lymphoma,Ibrutinib
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