Synthesis, Characterization, and Biological Activity of Silver Nanoparticles Synthesized from Aristolochia Bracteolata Lam.

The aim of this research is to analyze the antimicrobial activity and cytotoxicity of biologically synthesized silver nanoparticles against A549 cancer cell line. Silver nanoparticles were synthesized from the leaf extract of Aristolochia bracteolata. For the characterization of silver nanoparticles, Fourier transform infrared, high-performance liquid chromatography, and ultraviolet techniques were adopted. The silver nanoparticle was found to show better antimicrobial activity when compared to the crude extract of the plant. Noteworthy cytotoxic effects against A549 cell line were shown by the nanoparticles derived from the plant extract. Following the potential of biologically synthesized silver nanoparticles, they can be a valuable addition to the treatment of human laryngeal carcinoma and can be categorized as a potent anticancer agent.