Relation of Endothelin-1 to Abnormal Umbilical Doppler Waveform Studies in Pregnancies Complicated by IDDM and its Relation to the Neonatal Outcome

Hala A. Youssef,Ayman F. Armaneous, Hatem M. Hasan,Eman R. Youness,Marwa W. Abouelnaga

Biomedical and Pharmacology Journal（2020）

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摘要

Introduction Endothelin-1 (ET-1) seems to act as a local paracrine signal rather than a circulating hormone. Its effects are mediated by specific, membrane- bound receptors, which are detectable in high concentrations in the fetoplacental tissue. ET-1 causes an initial transient fall in blood pre

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umbilical doppler waveform studies,pregnancies

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