A Computing System for Discovering Causal Relationships Among Human Genes to Improve Drug Repositioning
IEEE Transactions on Emerging Topics in Computing(2021)
Abstract
The automatic discovery of causal relationships among human genes can shed light on gene regulatory processes and guide drug repositioning. To this end, a computationally-heavy method for causal discovery is distributed on a volunteer computing grid and, taking advantage of variable subsetting and stratification, proves to be useful for expanding local gene regulatory networks. The input data are ...
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Key words
Drugs,Prostate cancer,Organisms,Gene expression,Arteries
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