Examining the effects of atopic disease on concussion recovery: a preliminary investigation to inform personalized care

Background: Predicting time-to-recovery in pediatric concussion patients is key to advancing the treatment paradigm of pediatric concussion from a reactive to proactive precision and personalized medicine approach. Recent epidemiologic research indicates a possible mechanistic overlap between concussion and atopic disease (i.e., allergic rhinitis, asthma, and eczema) via pathways implicated in the inflammatory response. The purpose of this study was to examine patients with concussion and atopic disease comorbidity to better elucidate mechanisms that underlie protracted recovery and better predict return to play (RTP) timelines following concussion injury. Method: Data from …