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The Use Of Pre-Endoscopic Intravenous Proton Pump Inhibitors (Ppis) Had No Impact On Clinical Outcomes In Acute Upper Gastrointestinal Bleeding: A Prospective Multicenter Italian Cohort Study

R. Marmo,M. Soncini,C. Bucci,R. Bennato,F. Cipolletta,L. Orsini,L. Amitrano,F. Parente,S. Bargiggia,A. Paterlini,P. Cesaro,A. Bizzotto,B. Germana,L. G. Cavallaro,R. De Franchis,A. Dell'Era,G. Costamagna,M. E. Riccioni,C. Marmo,A. Tortora,M. Manno,S. Mangiafico,R. Conigliaro,G. Bresci,S. Metrangolo,A. Merighi,V. Boarino,S. Segato,M. Parravicini,L. Purita,A. Chirico,G. Imperiali,D. Spotti,F. Esposito,P. Borgheresi,F. R. De Filippo,G. Baldassarre,M. Franceschi,A. Nucci,F. De Nigris,L. Ferraris,A. Zambelli,C. Londoni,A. Repici,A. Anderloni,M. De Matthaeis,O. Triossi,M. A. Bianco,G. Rotondano,R. Lamanda,A. Lauri,C. De Fanis,P. Di Giorgio,R. Pumpo,L. Furio,A. Russo,A. Andriulli,G. Napolitano,L. M. Montalbano,F. Bazzoli,R. M. Zagari,E. Buscarini,L. Cipolletta,D. Conte,G. Spinzi,E. Di Giulio,A. Balzano

Digestive and Liver Disease（2020）

Cited 0|Views73
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Abstract
Aims Incidence of hospital admission for acute upper gastrointestinal bleeding (AUGIB) has decreased by 20% during the past 10 years, due to the changing epidemiology. The use of pre-endoscopic intravenous proton pump inhibitors (PPIs), currently recommended, is debated. Aim to verify if the use of pre-endoscopic PPIs improves the death and outcomes rate in these patients
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Key words
acute upper gastrointestinal bleeding,proton pump inhibitors,clinical outcomes,pre-endoscopic
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