Wall Shear Stress and Plaque Vulnerability Computational Fluid Dynamics Analysis Derived From cCTA and OCT

Takayoshi Toba, Hiromasa Otake, Gilwoo Choi, Hyun Jin Kim, Hiroyuki Onishi, Yoichiro Sugizaki, Ryo Takeshige, Akira Nagasawa, Yuichiro Nagano, Yoshiro Tsukiyama, Kenichi Yanaka, Hiroyuki Yamamoto, Hiroyuki Kawamori, Shumpei Mori, Masahito Kawata, Charles A. Taylor, Ken-ichi Hirata

JACC: Cardiovascular Imaging（2021）

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摘要

The heterogeneity of coronary atherosclerosis supports the hypothesis that local hemodynamic factors such as wall shear stress (WSS) influence the initiation and progression of atherosclerosis. Recent clinical studies investigating the relationship between WSS and atherosclerotic progression relied

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