A new heterocyclic compound: crystal structure and anticancer activity against human lung adenocarcinoma cells

New heterocyclic compound (S)-3-(4-(5-bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran ( 1 ), designed by utilizing 5-bromo-2-chlorobenzoic acid ( 2 ) as the starting material, is obtained by the organic synthesis and then characterized by single crystal X-ray crystallography, 1 H NMR and IR spectroscopy. In the biological study, the CCK-8 assay is performed to evaluate the inhibitory effect of the compound on SPC-A-1 human lung adenocarcinoma cells in vitro by measuring the cancer cell viability. Then, the anticancer activity of the compound is also confirmed by the in vivo xenograft experiment by measuring the mice body weight and the cancer volume.