Genomics and proteomics in venous thromboembolism: building a bridge toward a rational personalized medicine framework.
SEMINARS IN THROMBOSIS AND HEMOSTASIS(2007)
Abstract
Venous thromboembolism is a major health care problem worldwide and is sustained by a multifactorial pathogenesis where both congenital and acquired causes contribute. It is increasingly being highlighted that a reliable approach based on genomics and proteomics might be effective to construct a rational personalized medicine framework that can be applied in the preclinical, clinical, and therapeutic settings of venous thrombosis. The aim of this review is to provide a concise description of the current and future applications of genomics and proteomics in this challenging pathology.
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Key words
diagnosis,genomics,proteomics,therapy,venous thromboembolism
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