SOX2 Mediates Carbon Nanotube-Induced Fibrogenesis and Fibroblast Stem Cell Acquisition

Chayanin Kiratipaiboon,Maria Voronkova,Rajib Ghosh,Liying Wang Rojanasakul,Cerasela Zoica Dinu,Yi Charlie Chen,Yon Rojanasakul

ACS Biomaterials Science & Engineering（2020）

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摘要

Certain nano-sized particles like carbon nanotubes (CNTs) are known to induce pulmonary fibrosis, but the underlying mechanisms are unclear, and efforts to prevent this disease are lacking. Fibrobl...

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关键词

nanomaterial, fibrogenicity, myofibroblasts, self-renewal

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