PHYTOMOLECULES OF Bacopa monnieri DISPLAY POSITIVE AFFINITY FOR STEROL 14-ALPHA-DEMETHYLASE OF Trichophyton sp: POSSIBLE PREVENTIVE AND THERAPEUTIC USAGE IN TINEACAPITIS

Trichophyton sp causes Tineacapitis. Strikingly, Tineacapitis occurs primarily during specific molecular events, thus acting as a potential clinical biomarker. Further, Tineacapitis may also activate further downstream events, supporting the detrimental phase. To restrict the activity of Tineacapitis, several bio molecules can be deployed, of which the phytochemicals can be the best alternative. Molecular docking-based screening of a few phytochemicals revealed that the phytochemicals effectively associate with the active site of the sterol14-alpha-demethylase of Trichophyton sp and hence bears diagnostic and therapeutic potentials against Tineacapitis.