Framework of Computational Intelligence-Enhanced Knowledge Base Construction: Methodology and A Case of Gene-Related Cardiovascular Disease

Knowledge base construction (KBC) aims to populate knowledge bases with high-quality information from unstructured data but how to effectively conduct KBC from scientific documents with limited preknowledge is still elusive. This paper proposes a KBC framework by applying computational intelligent techniques through the integration of intelligent bibliometrics—e.g., co-occurrence analysis is used for profiling research topics/domains and identifying key players, and recommending potential collaborators based on the incorporation of a link prediction approach; an approach of scientific evolutionary pathways is exploited to trace the evolution of research topics; and a search engine incorporating with fuzzy logics, word embedding, and genetic algorithm is developed for knowledge searching and ranking. Aiming to examine and demonstrate the reliability of the proposed framework, a case of gene-related cardiovascular diseases is selected, and a knowledge base is constructed, with the validation of domain experts.