Suspected Case of Drug-Induced Acute Respiratory Distress Syndrome Following Trimethoprim-Sulfamethoxazole Treatment.
Journal of Pediatric Intensive Care(2020)
摘要
In this article, we reported the case of a child patient who was admitted to our PICU for severe acute respiratory distress syndrome (ARDS) while being treated with trimethoprim-sulfamethoxazole (TMP-SMX) for osteomyelitis. Based on the timing of exposure, lack of alternative explanations, and clinical course similar to previously described cases, we suspect that TMP-SMX may have triggered ARDS. Despite meeting criteria for extracorporeal membrane oxygenation cannulation, conservative management and lung recruitment with high-frequency percussive ventilation could avoid the latter.
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关键词
acute respiratory distress syndrome,trimethoprim,percussive ventilation
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