Effective Synthetic Approach to 4-Arylpyridine-2,6-dicarboxylic Acids

O. V. Shabunina,D. N. Kozhevnikov,D. S. Kopchuk,G. V. Zyryanov, A. I. Suvorova,V. L. Rusinov,O. N. Chupakhin

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY（2020）

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摘要

A convenient synthetic route to 4-arylpyridine-2,6-dicarboxylic acid has been proposed on the basis of substituted benzaldehydes according to the Kröhnke method, followed by oxidation of methyl group.

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关键词

pyridine-2,6-dicarboxylic acids,Krohnke method,heterocyclization,oxidation

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