Eclipta alba L. Derived Phytochemicals against Escherichia coli Causing Diarrhea

Krishna Rani, Aischarya Mohanty, Sagarika Parida, Manisha Mohanty, Subhashree Sahu, Sanchayita Nayak, Sutapa Mohanty

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL（2020）

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摘要

Phytochemicals from Eclipta alba L. plant extract are traditionally used to cure Diarrhea. It is caused by Escherichia coli. Molecular docking method applied using "Biovia Discovery Studio". "High positive values of -CDOCKER energy and -CDOCKER interaction energy" suggested that Pentadecanone can effectively deactivate the alcohol dehydrogenase enzyme (protein database code 4GKV) thereby interrupting the life cycle of the organism.

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关键词

Phytochemical,Eclipta alba L.,Escherichia coli,diarrhea

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