Nigella sativa Derived Phytochemicals against Cough

Diptiprajnya Sahoo,Minati Nayak,Sidhartha Ray,Mukundjee Pandey,Kalpita Bhatta, Sushree Susmita Palei, Debasmita Rautaray

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL（2020）

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摘要

Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using "Biovia Discovery Studio". "High positive values of - CDOCKER energy and -CDOCKER interaction energy" suggested that p-cymene can effectively deactivate the adenylate cyclase thereby interrupting the life cycle of the organism.

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关键词

Phytochemicals,Nigella sativa,Bordetella pertussis,cough

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