Eclipta alba Derived Phytochemicals against Jaundice

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL(2020)

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摘要
Phytochemicals otherwise known as secondary metabolites means the small organic molecules that are not essential for growth, development and reproduction but can protect from various diseases. Intact these phytochemicals are the key source of medicine. Secondary metabolites from Eclipta alba plant extract are traditionally used to cure Jaundice which is caused by Leptospira interrogans. The curative property of Eclipta alba against Leptospira interrogans was proved by molecular docking method in "Biovia Discovery Studio". "High positive values of - CDOCKER energy and -CDOCKER interaction energy" recommended that pentadecan, heptadecane, 6,10,14-trimethyl-2-petadecanone can successfully deactivate the thioredoxin-disulfide reductase enzyme thereby disrupting the cellular function as well as the lifecycle of causative organism.
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关键词
Phytochemical,Eclipta alba,Leptospira interrogans,jaundice
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